Pharmacology for the Future Science, Drug Development and Therapeutics / July1(Sun)-6(Fri),2018 Kyoto International Conference Center Kyoto, Japan

Scientific Program

As of April 10, 2017 - subject to change

Opening Lecture

Tasuku Honjo, M.D., Ph.D.


Tasuku Honjo, M.D., Ph.D.
Kyoto University, Japan

Plenary Lecture

Shinya Yamanaka, M.D., Ph.D.

Recent Progress in iPS Cell Research and Application

Shinya Yamanaka, M.D., Ph.D.
Kyoto University, Japan

Karl Deisseroth, M.D., Ph.D.


Karl Deisseroth, M.D., Ph.D.
Stanford University, USA

Nancy J. Brown, M.D.

The Cardiovascular Effects of Peptidase Inhibition

Nancy J. Brown, M.D.
Vanderbilt University Medical Center, USA

Adam Cohen, M.D., Ph.D.

Drug development as an outcome of integration of basic and clinical pharmacology,

Adam Cohen, M.D., Ph.D.
Center for Human Drug Research, The Netherlands

Tang Prize Lecture

Feng Zhang, Ph.D.

Genome Engineering: Technologies and Applications

Feng Zhang, Ph.D.
McGovern Institute for Brain Research, USA

Analytical Pharmacology Lecture

Bryan L. Roth M.D., Ph.D.

Towards a molecular understanding of drug action at GPCRs

Bryan L. Roth M.D., Ph.D.
Department of Pharmacology, University of North Carolina Chapel Hill School of Medicine, USA

Cutting Edge Lecture

Confirmed Speakers (Presentation themes are tentative.)

Alphabetical order

  1. Lipid mediators: function and therapeutic target for ocular diseases Makoto AiharaDepartment of Ophthalmology, The University of Tokyo, Japan
  2. Ethics and cutting-edge research design Christiaan B BrinkSchool of Pharmacy, North-West University, South Africa
  3. Structure, Function and Pharmacology of Na+ and Ca2+ Channels at Atomic Resolution William A. CatterallDepartment of Pharmacology, University of Washington, USA
  4. Differential clinical impacts of oxidative stress and nitrosative stress:
    Therapeutic implications
    Samuel H.H. ChanInstitute for Translational Research in Biomedicine, Chang Gung Memorial Hospital, Taiwan
  5. GPCR Allostery and Bias in Modern Pharmacology:
    Structural, pharmacological and clinical implications
    Arthur ChristopoulosMonash Institute of Pharmaceutical Sciences, Monash University, Australia
  6. Neurobiology of Stress, Depression, and Antidepressants:
    Rapid Remodeling of Synaptic Connections
    Ronald S. DumanDepartment of Psychiatry, Yale University School of Medicine, USA
  7. Systems Pharmacology and Translational Therapeutics Garret A. FitzgeraldPerelman School of Medicine, University of Pennsylvania, USA
  8. Drug Discovery for Neglected Diseases Ian GilbertDrug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, UK
  9. Future of Pharmacometrics Joga GobburuProfessor of Pharmacy Practice and Science Director, Center for Translational Medicine University of Maryland, USA
  10. TBA John A. HartleyUCL Cancer Institute, USA
  11. Molecular imaging for diagnosis and treatment of neurodegenerative disorders at a prodromal stage Makoto HiguchiNational Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Japan
  12. Cost-effectiveness Analysis for Health Policy Making in Japan Shunya IkedaSchool of Medicine, International University of Health and Welfare, Japan
  13. Positron Emission Tomography of Human Brain can Monitor Neuroinflammation and cAMP Signaling: Applications to Alzheimer's Disease and Depression Robert B. InnisNational Institute of Mental Health, USA
  14. Human pluripotent stem cells in neurological disease modeling and drug discovery Haruhisa InoueCiRA, Kyoto University, Kyoto, Japan
  15. Pharmacokinetic changes across the developmental trajectory Shinya ItoHospital for Sick Children, University of Toronto, Canada
  16. Molecular Mechanism of Type 2 Diabetes: Perspectives from Insulin Receptor and Adiponectin Receptor Actions Takashi KadowakiDepartment of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Toyo, Japan
  17. Microbiome and Epigenetic Effects on Xenobiotic Processing Genes Curtis D. KlaassenUniversity of Washington, USA
  18. Future of regulatory science in drug regulation Tatsuya KondoPharmaceuticals and Medical Devices Agency (PMDA), Japan
  19. Therapeutic Validation of Rasna Panchaka, Poly herbal formulation and ksheer pak by ‘Reverse Pharmacology (RP)’ Tool B. Dinesh KumarHOD Drug Toxicology Division, National Institute of Nutrition, India
  20. Biologics versus small molecules in treatment of systemic autoimmune diseases Masataka KuwanaDepartment of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Japan
  21. Unconventional Secretion of Membrane Protein Min Goo LeeYonsei University, College of Medicince, Korea
  22. Prescribing safety assessment: ensuring competency of new doctors to use medicines Simon MaxwellUniversity of Edinburgh, UK
  23. TBA Stephen B. McMahonKing's College London, UK
  24. RANKL-From basic discovery to clinical application Josef PenningerIMBA-Institute of Molecular Biotechnology, Austria
  25. Control of immune responses by regulatory T cells Shimon SakaguchiDepartment of Experimental Immunology, WPI Immunology Frontier Research Center, Osaka University, Japan
  26. Phospholipids metabolism in health and disease Takao ShimizuDepartment of Lipid Signaling, National Center for Global Health and Medicine/University of Tokyo Faculty of Medicine, Japan
  27. The Role of Public Sector Research in the Discovery of Drugs and Vaccines – an Update Ashley J. StevensFocus IP Group, LLC, USA
  28. Rethinking Sodium Metabolism Jens M. TitzeDivision of Clinical Pharmacology, Vanderbilt University Medical Center, USA
  29. Structural biology of P-type ATPases Chikashi ToyoshimaInstitute of Molecular and Cellular Biosciences, The University of Tokyo, Japan
  30. NSAID-induced gastrointestinal (GI) damage and the design of GI-sparing NSAIDs John L. WallaceDepartment of Physiology & Pharmacology, University of Calgary, Canada
  31. Brain-imaging for the treatment of psychiatric diseases Shigeto YamawakiDepartment of Psychiatry and Neurosciences, Hiroshima University/ Center of Innovation(COI), Japan
  32. TBA Baofeng YangDepartment of Pharmacology, College of Pharmacy, Harbin Medical University, China
  33. Pharmacological Action and Mechanism of Traditional Chinese Medicine Yongxiang ZhangBeijing Institute of Pharmacology and Toxicology, China


*Symposia titles are tentative.

1. Drug design based on 3D microstructure of receptors
Organizer:Yuji Ikegaya The University of Tokyo, Japan
2. Alzheimer's disease; toward very early diagnosis and treatment
Organizer:Takeshi Iwatsubo Department of Neuropathology, Graduate School of Medicine, The University of Tokyo, Japan
3. Shortened life span in patients with schizophrenia: Life style related problems and clinical pharmacology of antipsychotics
Organizer:Kazutaka Shimoda Department of Psychiatry, Dokkyo Medical University, Japan
4. Novel approaches towards understanding psychiatric disorders: inflammation in the brain and periphery
Organizer:Tomoyuki Furuyashiki Division of Pharmacology, Kobe University Graduate School of Medicine, Japan
5. Brain-Gut Axis
Organizer:Ludmila Filaretova Pavlov Institute of Physiology, Russia
6. Transformative technologies at the forefront of brain research
Organizer:Haruhiko Bito Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Japan
7. Ca2+ signaling in health and disease
Organizers:Haruhiko Bito Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Japan
Grey Stephens University of Reading , UK
8. Novel regulations and functions of dopaminergic systems towards understanding psychiatric disorders
Organizer:Tomoyuki Furuyashiki Division of Pharmacology, Kobe University Graduate School of Medicine, Japan
9. Alpha-synuclein in Parkinson's disease
Organizer:Masahiro Nomoto Ehime University, Japan
10.Recent advances in the development of subtype-selective and signaling-biased drugs for D2-like dopamine receptors: towards improved therapeutics for neuropsychiatric disorders
Organizer:David R. Sibley Molecular Neuropharmacology Section National Institute of Neurological Disorders & Stroke/NIH, USA
11.Emerging therapeutic targets against autism spectrum disorder
Organizer:Chan Young Shin Department of Pharmacology, School of Medicine, Konkuk University, Korea
12.Mechanisms of maladaptive plasticity in animal models of neuropsychiatric disorders
Organizer:Maurizio Popoli Department of Pharmacological and Biomolecular Sciences - University of Milano, Italy
13.The function and pharmacology of the neuronal renin-angiotensin system
Organizers:Clare Stanford UCL IRIS, UK
Mark Tricklebank Centre for Neuroimaging Sciences, Institute of Psychiatry and Psychology and Neuroscience, King’s College London, UK
14.ADHD and Substance Use Disorders: epidemiology, neurobiology and treatment
Organizer:Wim van den Brink Department of Psychiatry, Academic Medical Center University of Amsterdam, The Netherlands
15.Pain Sensor
Organizer:Yasuo Mori Graduate School of Engineering, Kyoto University, Japan
16.Central Pain and Translation
Organizer:Fusao Kato Department of Neuroscience, Jikei University School of Medicine, Japan
17.Pharmacology and Clinical Pharmacology about Inflammation and the Development of Atherosclerosis
Organizer:Hiroshi Watanabe Department of Clinical Pharmacology and Therapeutics, Hamamatsu University School of Medicine, Japan
18.Therapeutic strategy to enhance intrinsic resistance in cardiovascular system
Organizer:Motohiro Nishida Division of Cardiocirculatory Signaling Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Japan
19.New therapeutic approach for cardiorenal syndrome-integration of basic and clinical Pharmacological evidence
Organizer:Akira Nishiyama Department of Pharmacology, Kagawa University Medical School, Japan
20.Recent advances in the molecular and cellular understanding of heart failure--Toward novel therapeutic strategies
Organizer:Yasushi Fujio Laboratory of Clinical Science and Biomedicine Graduate School of Pharmaceutical Sciences, Osaka University, Japan
21.Hypertension: New developments in understanding and management
Organizers:David Webb University of Edinburgh, UK
Bean Dhaun University of Edinburgh, UK
22.Cutting edge of calcium permeable ion channels in diseases as potential targets of drug discovery
Organizers:Yuji Imaizumi Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan
David J. Beech University of Leeds, UK
23.Endothelial Mechanosensing in Vascular Physiology and Disease
Organizers:Naoki Mochizuki National Cerebral and Cardiovascular Center Research Institute, Japan
Stefan Offermanns Max Planck Institute for Heart and Lung Research, Germany
24.Lower Urinary Tract Dysfunction Update: New Insight into Pharmacological Mechanisms1
Organizer:Hidehiro Kakizaki Department of Renal and Urologic Surgery, Asahikawa Medical University, Japan
25.New pharmacological approaches for renal diseases
Organizer:Akira Nishiyama Department of Pharmacology, Kagawa University Medical School, Japan
26.Roles of Bioactive Lipids in Inflammatory Diseases
Organizers:Yukihiko Sugimoto Kumamoto University, Japan
Masataka Majima Department of Pharmacology, Kitasato University School of Medicine, Japan
27.Advances in molecular targeting therapy for rheumatoid arthritis
Organizer:Masayoshi Harigai Division of Epidemiology and Pharmacoepidemiology, Institute of Rheumatology, Tokyo Women’s Medical University, Japan
28.Immunology and Inflammation
Organizer:Satoshi Uematsu Department of Mucosal Immunology, School of Medicine, Chiba University, Japan
29.Molecular targets and imaging studies in bone diseases
Organizer:Hiroshi Takayanagi Department of Immunology Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Japan
30.New Controllers of Inflammation: What are the hottest targets?
Organizer:Francesca Levi-Schaffer The Hebrew University of Jerusalem, Israel
31.Translational Research in GI Pharmacology - Novel therapeutic strategy in GI diseases -
Organizer:Koji Takeuchi Kyoto Pharmaceutical University, Japan
32.Present status and future perspective of gastric acid inhibitor
Organizer:Takahisa Furuta Hamamatsu University School of Medicine, Japan
33.iPS cells and disease
Organizer:Haruhisa Inoue Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Japan
34.Humanized Mouse Models and iPSC as tools to study drug toxicity
Organizer:Darrell R. Abernethy US Food and Drug Administration/Johns Hopkins University School of Medicine, USA
35.Innovations in Overcoming Diabetes and Complications
Organizer:Momir Mikov Department of Pharmacology and Toxicology, University of Novi Sad, Serbia
36.Role of mitochondria and oxidative stress in metabolic syndrome
Organizer:Julie Y.H. Chan Kaohsiung Chang Gung Memorial Hospital, Taiwan
37.Novel Therapeutic Strategies for Respiratory Diseases
Organizer:WS Fred Wong The National University of Singapore, Yong Loo Lin School of Medicine, Singapore
38.Understanding living systems by extensive analyses of all cells
Organizer:Hiroki R. Ueda Graduate School of Medicine, University of Tokyo/ RIKEN QBiC, Japan
39.Systems Biology and Drug Targeting
Organizer:Mariko Okada Laboratory of Cell Systems, Institute for Protein Research, Osaka University, Japan
40.Targeting antioxidant defence system in redox diseases
Organizer:Mi-Kyoung Kwak The Catholic University of Korea, College of Pharmacy, Korea
41.Photobiology: understanding of biological systems by illuminating and controlling biological functions by light
Organizers:Ryoichiro Kageyama Kyoto University Institute for Virus Research, Japan
Cyril Goudet Institut de Génomique Fonctionnelle, France
42.European & Asian training initiatives to improve safe and effective use of medicines in modern healthcare
Organizer:Shinichiro Ueda University of the Ryukyus, Japan
43.Experiences and models for strengthening pharmacological research, teaching and services in resource strained countries
Organizer:Collen Masimirembwa African Institute of Biomedical Science & Technology (AiBST), Zimbabwe
44.IPE: Educating a New Generation of Healthcare Professionals to Prescribe Medications Safely and Effectively
Organizer:Kelly Dowhower Karpa Pennsylvania State University College of Medicine, USA
45.Introducing the IUPHAR Pharmacology Education Project -
Organizer:John L. Szarek The Commonwealth Medical College, USA
46. Frontiers in approaching retinal research - The current status and future in development of therapeutic strategies based on genetic and iPS methods-
Organizer:Hideaki Hara Gifu Pharmaceutical University, Molecular Pharmacology , Japan
47.Novel targets and biomarkers for Anticancer Therapeutics
Organizer:Atsushi Ohtsu National Cancer Center Japan, Japan
48.Cancer Drug Resistance
Organizer:Mi-Kyoung Kwak The Catholic University of Korea, College of Pharmacy, Korea
49.Therapeutic manipulation of RNA/DNA for genetic diseases
Organizer:Masatoshi Hagiwara Department of Anatomy and Developmental Biology, Kyoto University Graduate School of Medicine, Japan
50.Multidisciplinary Approach on Molecular Bio-imaging from Basic to Clinical Pharmacological Studies
Organizer:Kazuhiko Yanai Department of Pharmacology, Tohoku University School of Medicine, Japan
51.Vaccine Drug Diagnostic Development for the control of Emerging Infectious Diseases
Organizer:Kouichi Morita NEKKEN, Nagasaki Univ, Japan
52.All for Global Health, Global Health for All
Organizer:Kenji Hirayama NEKKEN、Nagasaki University, Japan
53.Optimising drug selection and dosage in treating infectious diseases in children and pregnant women in Africa
Organizer:Lars L. Gustafsson Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Sweden
54.New Drugs for Emerging Infectious Disease
Organizer:Mauro Teixeira Department Biochemistry and Immunology, Universidade Federal de Minas Gerais, Brazil
55.Globalization of Traditional Asian Medicine
Organizer:Haruki Yamada Kitasato University, Japan
56.Ameliorating effects of traditional Chinese medicine on ischemia/reperfusion-induced cerebral microcirculatory disturbances and neuron damage
Organizer:Jing-Yan Han Department of Integration of Chinese and Western Medicine, Peking University Health Science Center, China
57.Pharmacological investigation in new drug discovery
Organizer:Guanhua Du Institute of Materia Medica, Chinese Academy of Medical Sciences, China
58.Network pharmacology
Organizer:Wenxia Zhou Beijing Institute of Pharmacology and Toxicology, China
59.Global clinical trials and ethnic factors
Organizer:Masahiro Tohkin Department of Regulatory Science, Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan
60.Role of database study in pharmacovigilance
Organizer:Kiyoshi Kubota NPO Drug Safety Research Unit Japan, Japan
61.Health Technology Assessment (HTA) for Smaller Countries: the central role of clinical pharmacology
Organizers:Phil Routledge Cardiff University, UK
David Webb University of Edinburgh, UK
62.Novel biomarkers, predictors and models for drug-induced liver injury
Organizer:Daniel Antoine University of Liverpool and MRC Centre for Drug Safety Science, UK
63.Toxicogenomics for accelerated and refined hazard identification of chemicals
Organizer:Jun Kanno Japan Bioassay Research Center Japan Organization of Occupational Health and Safety, Japan
64.Pharmacogenomics in drug therapy; future perspective, next generation of pharmacogenomics
Organizer:Ichiro Ieiri Kyushu University, Japan
65.Posttranslational modification of nuclear receptors as therapeutic targets
Organizer:InKyeom Kim Kyungpook National University School of Medicine, Korea
66.Pharmacogenomics in Special Populations
Organizers:Guilherme Suarez-Kurtz Brazilian Pharmacogenomics Network, Brazil
Andrew Somogyi University of Adelaide, Australia
67.Horizon of PMx
Organizer:Yuji Kumagaya Kitasato University Hospital Clinical Trial Center, Japan
68.Recent progress of immunosuppressant TDM
Organizer:Satohiro Masuda Department of Pharmacy, Kyushu University Hospital, Japan
69.Pharmacokinetic/-dynamic modelling
- Population PK/PD-models
- Physiology-based PK (PBPK) models
- PK/PD models: application in paediatrics
- PB/PK-modelling: regulatory aspects
Organizer:Petra A. Thürmann University Witten/Herdecke, HELIOS Hospital Wuppertal, Germany
70.The prediction of renal drug transport: a story with many tales
Organizer:Rosalinde Masereeuw Utrecht Institute for Pharmaceutical Sciences, Div. Pharmacology, The Netherlands
71.Innovative apprach to pediatric drug development and clinical practice
Topics include pharmacogenomics, pharmacometrics and new formulations.
Organizer:Hidefumi Nakamura National Center for Child Health and Development, Japan
72.Open Innovation for Drug Discovery
Organizer:Chikako Saotome Department of Drug Discovery Medicine, Kyoto University Graduate School of Medicine, Japan
73.System pharmacology of the AMPK-activated protein kinase
Organizers:A. Mark Evans University of Edinburgh, UK
 Graham Hardie University of Dundee, UK
74.Molecular pharmacology focused studies of calcium permeable ion channels: identifying new pharmacological targets and therapies
Organizer:Gregory Monteith The School of Pharmacy, The University of Queensland, Australia
Organizer:Supornchai Kongpatanakul National Doping Control Centre, Mahidol University, Thailand
76.Computational Pharmacology, Databases and Drug Discovery
Organizers:David Gloriam University of Copenhagen, Denmark
 Adam Pawson University of Edinburgh, UK
77.3D microtissues in drug discovery: mechanopharmacology
Organizer:Alastair Stewart Department of Pharmacology and Therapeutics, University of Melbourne, Australia
78.The BPS Focus on Pharmacology Project: Securing the future of Pharmacology & Clinical Pharmacology
Organizers:David Webb University of Edinburgh, UK
 Jonathan Bruun British Pharmacological Society, UK
79.Nutrient and Metabolite Sensing by GPCRs, or more broadly: Novel Natural Ligands and Functions of GPCRs
Organizers:Kazuwa Nakao Medical Innovation Center, Kyoto University Graduate School of Medicine, Japan
Stefan Offermanns Max Planck Institute for Heart and Lung Research, Germany
80.Cutting edge assay technologies for studying molecular and cellular pharmacology (joint symposium between BPS and ASCPT)
Organizers:Kevin Pfleger Harry Perkins Institute of Medical Research, Australia
Michelle Halls Monash Institute of Pharmaceutical Sciences, Australia
81.New insight into aquaporin function as drug targets
Organizer:Masato Yasui Keio University School of Medicine, Japan
82.GPCR and RhoA Signaling in Physiology and Disease
Organizer:Joan Heller Brown Department of Pharmacology, University of California, USA
83.Biased agonism at G protein-coupled receptors: The promise and the challenges
Organizer:Anthony P. Davenport Experimental Medicine and Immunotherapeutics, University of Cambridge, UK
84.African Indigenous Biodiversity: Gateway for Discovery
Organizer:Douglas Oliver Pharmacology for Africa, South Africa
Opening Symposium
Oral Sessions / Poster Sessions
Luncheon Seminars

Program at a Glance

July 1 - Opening Ceremony
Opening Lecture
Opening Symposium
Welcome Reception
July 2 Plenary Lecture
Cutting Edge Lectures
Oral Sessions
Poster Sessions
Luncheon Seminars
July 3 Plenary Lecture
Cutting Edge Lectures
Tang Prize Lecture
Oral Sessions
Poster Sessions
Luncheon Seminars
July 4 Plenary Lecture
Cutting Edge Lectures
Analytical Pharmacology Lecture
Oral Sessions
Poster Sessions
Luncheon Seminars
July 5 Plenary Lecture
Cutting Edge Lectures
Oral Sessions
Poster Sessions
Luncheon Seminars
Gala Dinner (Ticketed Event)
July 6 Symposia
Closing Ceremony

Congress Secretariat

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