Chair of the Department of Medicine Hugh J. Morgan Professor of Medicine and Pharmacology Physician-in-Chief
Nancy J. Brown, MD is Hugh Jackson Morgan Professor of Medicine and Pharmacology, Chair of the Department of Medicine, and Physician-in-Chief at Vanderbilt University School of Medicine. A graduate of Yale College and Harvard Medical School, Dr. Brown leads a translational research program that focuses on pharmacological strategies to prevent diabetes and end-organ damage in hypertension. Dr. Brown’s translational research focuses on enhancing pharmacological strategies to prevent cardiovascular injury in patients with hypertension and diabetes. Her group first described the contribution of endogenous bradykinin to the blood pressure lowering and fibrinoloytic effects of ACE inhibitors. They characterized the mechanisms whereby bradykinin stimulates t-PA release from the vascular endothelium. The group also elucidated beneficial vascular effect of ACE inhibitors and aldosterone receptor blockers in decreasing the synthesis of the inflammatory, prothrombotic, and profibrotic plasminogen activator inhibitor-1. Dr. Brown is an active member of the American Heart Association Council for High Blood Pressure and the American Society of Hypertension. Dr. Brown served on the NIH National Advisory Research Resources Council from 2007-2011 and currently serves on the National Heart, Lung, and Blood Advisory Council. Her honors include the American Society of Hypertension Young Scholar Award, American Federation for Clinical Research Outstanding Investigator Award, the Grant Liddle Award, the E.K. Frey - E. Werle Foundation Promotion Prize, the AHA Harriet Dustan Award, and membership in the American Society for Clinical Investigation and in Association of American Physicians. Dr. Brown is a fellow of the American Association for the Advancement of Science, and member of the National Academy of Medicine.