Feng Zhang obtained his A.B. degree in Chemistry and Physics from Harvard University and his Ph.D. degree from the Department of Bioengineering at Stanford University, where he worked in the lab of Karl Deisseroth on the development of optogenetics. In 2011, Zhang began his own lab at the Massachusetts Institute of Technology (MIT), pioneering the use of CRISPR-Cas systems as genome editing tools. He and his team successfully adapted the RNA-guided nuclease Cas9 for mammalian genome editing. Following this initial demonstration, the Zhang lab has continued to expand and refine Cas-based approaches, helping to create a robust genome engineering toolbox that is accelerating research around the world. He is currently a Core Member of the Broad Institute of MIT and Harvard, an Investigator of the McGovern Institute for Brain Research at MIT, and an Associate Professor in the Departments of Brain and Cognitive Sciences and Biological Engineering at MIT.